The human body has an endocannabinoid system — a natural system that maintains homeostasis or balance, in the body. The endocannabinoid system has CB1 and CB2 receptors. These are found throughout the body. CB1 receptors are generally located in the central and peripheral nervous system and CB2 receptors are generally found in the brain, immune system, and gastrointestinal system. CBD binds to these receptors creating changes and effects in the body
For a more detailed list of medications which use the P450 enzyme, see this list provided by the College of Physicians and Surgeons of British Columbia. Even as most common medications utilize this enzyme in their potency, it is important to note that CBD may have little to no effect on the drug depending on the patient, the medication, and the amount of CBD taken.
But because all these products are illegal according to the federal government, cannabis advocates are cautious. “By and large, the federal government is looking the other way,” says Paul Armentano, deputy director of the Washington, DC–based National Organization for the Reform of Marijuana Laws (NORML), but until federal laws are changed, “this administration or a future one could crack down on people who produce, manufacture, or use CBD, and the law would be on its side.”
I have been taking 50 Mg daily CBD oil with morphine (MS Contin) for almost 5 months with no problems. I actually have been able to decrease my morphine dosage to 2 times a day instead of 3 due to considerably less pain. I have also stopped taking every oral prescription med except the morphine. My morphine dosage was only 15 mg 3 times which is considered low. I sleep better, feel calmer, am not cold all the time and I hope to be able to discontinue the morphine. I live in a state that has legalized marijuana so I hope to grow some low THC to harvest my own oil.
Dana Scott is the Founder and CEO of Dogs Naturally Magazine. She also breeds award winning Labrador Retrievers under the Fallriver prefix. Dana has been a raw feeding, natural rearing breeder since the 90's and is a sought after speaker and outspoken advocate for natural health care for dogs and people. Dana works tirelessly to educate pet owners so they can influence veterinary medicine and change current vaccine, food and preventive health practices. Visit Dana's Labradors at Fallriver Labs
A study from 2016 worked with 214 people with epilepsy. The study participants added oral doses of 2 to 5mg of CBD per day to their existing anti-epilepsy medications. The study’s researchers monitored the participants for 12 weeks, recording any negative side effects and checking on the frequency of their seizures. Overall, participants had 36.5 percent fewer seizures per month. However, severe adverse effects were recorded in 12 percent of the participants.
Typically, CBD is taken as an adjunct treatment along with prescribed medications, either to counteract the pharmaceutical’s side effects or further aid in existing symptoms. However, patients must be careful in using CBD in conjunction with pharmaceutical drugs, as research has shown that CBD may cause some vital medications to become less effective, as a result of how CBD interacts with certain enzymes and proteins.
The reason so many people are interested in cannabis products that don’t make them high, proponents say, is that CBD helps with everything from pain and nausea to rheumatoid arthritis, cancer, Crohn’s disease, and dementia. CBD is anti-inflammatory, anti-anxiety, antibacterial, immunosuppressive, and more, says Joseph Cohen, DO, a cannabis doctor in Boulder, CO.
I experienced the same thing with the first supplier I used. I purchased the oil based on the price….i no longer do that. I research the company and talk to them about their process and base my decision on the purity of the product. There are now so many ways to take CBD’s that if one doesn’t seem to fit or has negative side effects, try another delivery option. Also, I would try changing the supplier and purchase only the best product that you can find or afford. I had a negative experience with one supplier where their product gave me a bad headache, I changed suppliers (little more expensive) and the headaches stopped.
There’s no definite amount that’s appropriate for everyone, but the ratio of CBD to THC will indicate how psychoactive the product is and if it’s legal in your state. The more CBD compared with THC, the less of a high, and vice versa. “Managing psychoactivity is key to successful cannabis therapy,” says Lee. “Amounts should be made clear on the label and lab-certified so people know what’s helping them and what’s not.”
Transparency: Moon Mother sends each batch of product to a third-party lab to be tested for potency as well as other contaminants. You can find all of these lab reports on the company’s website. They also added more information about their company processes to the website, so it’s easier to find important information about extraction and manufacturing.
Based in Los Angeles, Calm by Wellness plans to be among the largest hemp-growing and CBD extraction facilities in the world by the end of 2019. The company sources their hemp from Colorado and uses clean CO2 technology to extract their CBD and other cannabinoids (no THC though!). The company is also GMP and ISO9001 food-grade manufacturer certified.
Physically, the ECS is one of the most significant systems in the human body. It is made up of thousands of neurological receptors throughout the brain and body, all passing messages to one another in order for the body to function. The ECS is known to be responsible for a variety of motor functions, immune system functions, and nervous system functions as well. Through this intricate network of receptors, various enzymes, proteins, and other components pass signals to and from one another, thus helping us to physically adapt to changes.
We’ve already looked at some of the research behind CBD’s anti-inflammatory benefits — but its role in preventing inflammation may go well beyond treating pain. Scientists have known for a long time that chronic inflammation is related to the development of cancer, and multiple studies have linked taking anti-inflammatory drugs to a significant decrease in cancer development. CBD fills this role without the possible side effects of NSAIDs like Naproxen or Ibuprofen.
CBD is extracted from marijuana plants as either an oil or powder. These can be mixed into creams or gels. They can be put into capsules and taken orally, or rubbed on your skin. The multiple sclerosis drug nabiximols is sprayed as a liquid into your mouth. How CBD should be used depends largely on what it’s being used for. Talk to your doctor before using CBD oil. It hasn’t been approved by the U.S. Food and Drug Administration (FDA) for any medical uses, and it can have side effects.
It’s vital to know how and where hemp was grown. That’s because hemp is a bioaccumulator, meaning hemp absorbs contaminants from the soil while it grows. So if the soil it was grown on is not good, clean soil, then that plant might contain high levels of lead or mercury. When hemp is imported, it’s harder to ensure the hemp is grown responsibly, sustainably and without adding potential toxins to the products made from the crop. While it used to be that most CBD brands imported their hemp, today more and more brands use domestically grown hemp. We’ve also included some brands that use responsibly grown hemp imported from Europe.