CBD (cannabidiol) is a compound found in cannabis and hemp. THC (tetrahydrocannabinol) can also be found in cannabis. It’s this compound that gives marijuana its psychoactive properties. Most CBD oils are just that … the beneficial CBD without the THC. And they typically come from hemp, not marijuana. In short, your dog won’t get “high” from CBD oil … he’ll get the relaxation without the intoxication.
Though there are some topical treatments, cannabis oil is typically administered orally to dogs. It also can be used in conjunction with traditional medications and treatments. Emerging research suggests there can be “synergistic benefits” between marijuana and traditional medications, Richter says. “There are few, if any, known significant drug interactions that you really need to be concerned about.”
In the study, results suggested that the CYP3A4 enzyme was inactivated in many cases by dosages of CBD. This was due to the fact that CBD and the CYP3A4 enzyme had a defensive reaction to one another, thus causing the metabolites of CBD to become less effective as well. In other words, the CYP3A4 enzyme and CBD seem to “cancel out” the benefits of one another when CBD is taken simultaneously with certain medications.
The effects of CBD on receptors in the immune system may help reduce overall inflammation in the body. In turn, CBD oil may offer benefits for acne management. A human study published in the Journal of Clinical Investigationfound that the oil prevented activity in sebaceous glands. These glands are responsible for producing sebum, a natural oily substance that hydrates the skin. Too much sebum, however, can lead to acne.
A study published in 1986 in the International Journal of Neuroscience, examined the effects of CBD oil in 5 patients with dystonic movement disorders (muscle tremors and other forms of uncontrollable movements). CBD oil’s side effects “were mild and included hypotension [low blood pressure], dry mouth, psychomotor slowing [slowed thoughts or movements], lightheadedness, and sedation,” according to the study’s authors, Paul Consroe, Reuven Sandyk and Stuart R. Snider.
Vaping CBD oil is one of the preferred methods to ease side effects of diseases, illnesses, and ailments including Leukemia, all types of Cancers, stress, anxiety, joint pain, seizures, inflammation, sleep apnea, high blood pressure and the list goes on. There are many benefits to CBD vape oil. However, the effectiveness of CBD helping with these conditions (and many others) hasn’t yet been scientifically proven, and many trials are still in pre-clinical stage.
Like humans, animals can suffer from all manner of chronic pain, and this 2015 review of the scientific literature on chronic pain and cannabinoid usage found that seven out of eleven high-quality trials showed cannabinoids to have “a significant analgesic effect.” Researchers also reported that “several trials also demonstrated improvement in secondary outcomes (e.g., sleep, muscle stiffness, and spasticity).”
Each bottle contains 200 drops, and Provacan recently increased the size of the larger option by 20%. If you choose the 1200mg option, you receive 6mg of CBD per drop in the 10ml bottle. The company has also boosted the terpene profile of its oil along with levels of additional cannabinoids, including CBG, CBC, THCa, and CBDv – all non-psychoactive compounds that do not produce a high.